PASC Hair Restoration
Adult stem cells are most concentrated in fat tissue or adipose. Modern technology has enabled Dr. Singer to harvest these fat cells and concentrate and purify them in a centrifuge system. He then combines the fat cells with PRP to inject into the scalp to stimulate hair growth and stabilize further hair loss. This process is even more beneficial than just PRP alone because the stem cells continue to grow and enhance hair growth
There are a variety of factors that are a part of how the hair growth process occurs, and the process is very complex. Factors that contribute to hair growth include genetics, environmental issues, hormonal influences, nutrition, Health conditions, and autoimmune disorders (Infections, Iron deficiency, Metabolic issues)
The Basics of Hair Growth for Hair Restoration
People grow and lose their hair constantly. Our scalp is able to get rid of hair that is damaged or dead daily. If you have alopecia, you will not have new hair growth where your hair was lost. As people get older, they tend to lose their primary terminal hairs on their scalp and those hairs are replaced with vellus hairs, which are similar to the hair we have as a baby.
Hair Restoration Options
Fortunately, there are a variety of hair restoration techniques and cosmetic hair procedures that are available. A treatment plan will be customized for you since each situation is different. Recently, there has been an increasing interest in hair restoration by using the injection of Platelet rich plasma.
Platelet Rich Plasma (PRP) therapy has been FDA approved and utilized for over 30 years for advanced wound healing. Now, we are seeing exciting results with Platelet Rich Plasma treatment for hair growth. A patient’s blood is drawn and spun in a centrifuge to concentrate the platelets to a specific concentration effective for hair growth. The platelets are then activated and injected back into the scalp at the level of the hair follicles. This process stimulates the body’s own growth factors and stem cells to slow hair loss, reverse miniaturized hair to produce a strong, visible hair again, and if used at the time of a hair transplant, it encourages faster graft growth. This has been very effective for both men and women
Platelet Rich Plasma therapy is derived from the patient’s own blood serum. The patient’s blood is placed in a centrifuge where each part of the blood is separated. The platelet rich plasma is isolated and used to inject into the patient’s scalp. This PRP therapy is rich in growth factors, multiple other wound healing and new hair follicle stimulating cells. PRP has long been used for enhanced wound healing and joint restoration but has now been found to actually stimulate new hair growth. This therapy can be used in conjunction with the surgical hair restoration procedures or alone for patients electing not to have surgery. Non-surgically, several studies have shown increased hair density at 4 months lasting for approximately 11 months. Non-surgical injections of PRP are generally performed twice a year.
Another alternative is using a medication, such as Rogaine or Propecia. These two medications are the only medications that have been approved by the FDA for treating baldness. Both medications are more effective at maintaining hair that is already on your scalp than re-growing your hair. People who have used Propecia have reported having side effects, and some of those effects are permanent even if you stop using the product. Propecia also is unable to restore the large healthy follicles in androgenic alopecia.
During the last ten years or so, there has been great promise for being able to treat baldness by using stem cell technology. Scientists had previously thought that if someone suffered from hair loss, then they had a depletion of hair follicles and follicle stem cells that are needed to grow hair. However in 2011, Dr. George Cotsarelis, who is a professor of dermatology at the University of Pennsylvania, had a study published that showed that people who are bald actually have the same number of follicle stem cells as those who are not bald. Dr. Cotsarelis, along with his team, analyzed skin cells from people with androgenetic alopecia and looked at skin cells from both the bald and non-bald parts of the scalp. They utilized different markers to differentiate between the stem cells and hair follicle progenitor cells and they counted the number of each and determined that there was the same number of follicle stem cells in the skin of people who are bald as there were for people who were not bald.
If the stem cells in the scalp are unable to develop and become cells that can produce hair follicles, it may be an underlying cause of male-pattern baldness. If the researchers are able to determine the signals that can stimulate the stem cells and make them produce more hair follicle progenitor cells they may be able to get bigger hair follicles that are able to grow hair. There are studies showing that men who have male pattern baldness still have stem cells in follicle roots but their stem cells have lost the ability to regenerate hair. Scientists have discovered that follicle stem cells need to have a signal from the skin in order to grow hair but were not sure about where the source of that signal came from.
In 2011 also, there was a groundbreaking report from Yale that seemed to show the effectiveness of adipose that derived from stems cells to activate hair follicles that had been dormant so they can now grow new hair. The team at Yale observed that the fat layer expands when hair growth begins in a process that is called adipogenesis. The researchers discovered that there is a type of stem cell that is used in creating new fat calls, (adipose precursor cells), and they are necessary for regenerating hair in mice. They also found that these cells are able to produce signal molecules that are called platelet derived growth factor (PDGF), and those cells were needed to have hair growth in the mice. While we are not sure if PDGF has the same chemical signal effect for human hair growth, we do not that it is a powerful activator of human adult mesenchymal stem cells.
The PASC Protocol
PASC PROTOCOL is the study of the effects on the controlled micro-implantation of stromal vascular fraction that comes from the autologous human fat in the scalp of men who have alopecia. You can introduce controlled doses of fat that come from the autologous stem cells with an automatic micro-injection system. The micro-injection system is painless and can be done as an outpatient procedure under local anesthesia.
By micro implanting the stem cells and activating these cells, it is expected that men with alopecia will have their dormant follicles stimulated so they can grow new hair. If the degenerated follicle cells are able to grow new hair and can sustain that hair, we will be able to have the same successful hair regeneration effects that the mice had for humans. SVF and stem cells may still have an important role for more traditional hair transplant methods until we reach that time.
PASC Hair Transplantation
Hair transplantation is a safe, permanent solution to the problem of hair loss. Since the early 1950’s, the techniques used in hair restoration have evolved and matured to the point that the results of high-quality contemporary hair transplants look so natural that they’re virtually undetectable. Dr. Singer with more than 35 years of experience in hair restoration is a leader in the field and now combines his expertise in autologous stem cell transplantation and PRP in order to enhance the outcome of hair restoration.
At PASC, we use follicular unit techniques to imitate natural hair growth. Hairs grow in tiny groupings (known as follicular units) of just 1, 2, 3, or 4 hairs each. The PASC process begins with the removal of hair from the “donor area” at the back or sides of the patient’s head, where healthy hair follicles are most likely to be plentiful. The grafts of hair are then transferred in follicular units to the areas of the patient’s scalp where hair has become thin.
PASC’s expert hair restorations combine exacting medical techniques with a finely honed aesthetic sense. The creation of a truly natural-looking transplanted hairline requires an artist’s eye. The eye of an experienced plastic surgeon. In performing hair transplants, doctors must take many elements into account, including hair color, hair texture, and the unique direction of each patient’s natural hair growth pattern.
Hair Transplant Surgery
Hair restoration surgery is a simple outpatient procedure performed under local anesthetic. When you arrive at PASC, Dr. Singer will discuss your goals for the procedure and finalize the details of your hair transplant surgery. The hair in your donor area will be trimmed, and you’ll receive a local anesthetic. Then, your doctor will remove tissue from your donor area. Once the follicular units have been prepared for the graft, the doctor will position them on your scalp in the recipient area. After the first few days following a procedure, the typical patient experiences little or no discomfort. Once you’ve had surgery at PASC Hair Restoration, you’ll enjoy normal hair growth and a natural appearance.
Park Avenue Stem Cell is not offering stem cell therapy as a cure for any condition, disease, or injury. No statements or implied treatments on this website have been evaluated or approved by the FDA. This website contains no medical advice. All statements and opinions provided by this website are provided for educational and informational purposes only and we do not diagnose or treat via this website or via telephone. We are offering patient funded research to provide individual patients with Stromal Vascular Fraction that contains their own autologous stem cells and growth factors and the treatment centers provide surgical procedures only and are not involved in the use or manufacture of any investigational drugs.
Park Avenue Stem Cell does not claim that any applications, or potential applications, using autologous stem cells are approved by the FDA, or are even effective. We do not claim that these treatments work for any listed nor unlisted condition, intended or implied. It’s important for potential patients to do their own research based on the options that we present so that one can make an informed decision. Any decision to participate in our patient funded experimental protocols is completely voluntary.
ATTENTION: If you have ANY concern with stromal vascular fraction, any of our products, methods, website, or technique and think we may be violating any U.S. law, please contact us so that we can investigate the matter or concern immediately.
**Results of these treatments vary from individual to individual and it is not possible to predict or guarantee the outcome of any medical procedure.