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Future brain therapies for Parkinson’s possible with stem cell bioengineering innovation

 Scientists at Rutgers and Stanford universities have created a new technology that could someday help treat Parkinson’s disease and other devastating brain-related conditions that affect millions...

How to grow human bones in a lab

(CNN) Doctors perform almost a million bone-graft surgeries each year in the United States, and despite many advancements in medicine, the procedure remains surprisingly primitive. In most...

RNA-binding proteins in mouse male germline stem cells: a mammalian perspective

Abstract Adult stem cells that reside in particular types of tissues are responsible for tissue homeostasis and regeneration. Cellular functions of adult stem cells are intricately...

Wnt/?-catenin signaling in heart regeneration

Abstract The ability to repair damaged or lost tissues varies significantly among vertebrates. The regenerative ability of the heart is clinically very relevant, because adult teleost...

Stem cell aging in adult progeria

 Abstract Aging is considered an irreversible biological process and also a major risk factor for a spectrum of geriatric diseases. Advanced age-related decline in physiological functions,...

The interplay between metabolic homeostasis and neurodegeneration: insights into the neurometabolic nature of amyotrophic lateral sclerosis

 Abstract Amyotrophic lateral sclerosis (ALS) is a fatal, neurodegenerative disease that is characterized by the selective degeneration of upper motor neurons and lower spinal motor neurons,...

Stem cell therapy for amyotrophic lateral sclerosis

Abstract Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the loss of motor neurons. Currently, no effective therapy is available to treat ALS,...

Reprogramming somatic cells to cells with neuronal characteristics by defined medium both in vitro and in vivo

Background Currently, direct conversion from somatic cells to neurons requires virus-mediated delivery of at least one transcriptional factor or a combination of several small-molecule compounds. Delivery...

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