Asthma is a common chronic inflammatory disease of the airways characterized by symptoms including wheezing, coughing, chest tightness, and shortness of breath, reversible airflow obstruction, and bronchospasm. Asthma is clinically classified according to the frequency of symptoms, forced expiratory volume in 1 second (FEV1), and peak expiratory flow rate. Asthma may also be classified as atopic (extrinsic) or non-atopic (intrinsic). It can be exercised induced or occupational. Asthma affects an estimated 300 million people worldwide and caused 250,000 deaths in 2009.
Chronic obstructive pulmonary disease (COPD) is one of the most common lung diseases. It makes it difficult to breathe. There are two main forms of COPD: chronic bronchitis, which involves a long-term cough with mucus, and emphysema, which involves destruction of the lungs over time.
Congestive Heart Failure and Cardiomyopathy
Congestive heart failure (CHF) is responsible for many one million hospitalizations in the U.S. and is considered the main cause or contributor to 53,000 deaths each year in the United States. CHF is associated with cardiomyopathy. Cardiomyopathy (deterioration in heart muscles) is commonly caused by coronary vessel disease but can also be due to infection and other causes. In this condition, the heart loses its ability to pump blood efficiently.
Post MI (Myocardial Infarction)
Myocardial infarction (also known as heart attack) is responsible for significant cardiac destruction due to ischemia (lack of blood flow). This can lead to further or recurrent infarct and chronic angina. This problem is caused most commonly by coronary vessel disease which is very common in the United States and associated with significant morbidity.
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