Erectile Dysfunction


What is Erectile Dysfunction or ED?

Erectile Dysfunction, sometimes called ‘impotence’, is the repeated inability to get or keep an erection firm enough for sexual intercourse. The word ‘impotence’ may also be used to describe other problems that interfere with sexual intercourse and reproduction, such as lack of sexual desire and problems with ejaculation or orgasm. Using the term erectile dysfunction makes it clear that those other problems are not involved.

Damage to nerves, arteries, smooth muscles, and fibrous tissues, often as a result of a disease, is the most common cause of erectile penile dysfunction. Diseases such as diabetes, kidney disease, chronic alcoholism, multiple sclerosis, atherosclerosis, vascular disease, and neurologic disease, account for about 70 percent of erectile dysfunction cases. Between 35 and 50 percent of men with diabetes, experience erectile dysfunction.

At Park Avenue Stem Cell Therapy Center we believe that cost should not be an obstacle to getting your quality of life back. We put these procedures within reach of most budgets.

What causes ED?

Defects preventing an appropriate erectile tissue response can interfere with reproductive capability. Erection of the penis is a hemodynamic action that tissue of the corpora cavernosa and the corpus spongiosum. This tissue consists of smooth muscle, endothelial cells, fibroblasts, and nerves that interact in order to enhance and maintain an accessory blood supply causing erection. Given the need for the blood flow during this response, it is clear that vascular insufficiency can decrease erectile capability.

In fact, vascular insufficiency may be a common pathology of erectile dysfunction. It is estimated that up to 80% of the cases of erectile dysfunction can be attributed at least in part to a reduced blood flow, typically due to an underlying vascular disease.

Pharmacological methods have been used to treat erectile dysfunction including the use of vasodilators. Such vasodilators include Viagra and Cialis. However, vasodilators induce only a temporary response and are not effective in many patients due to the underlying endothelial damage. Not to mention the fact that these medicine can have serious side-effects including heart attack, stroke and may even cause death.

Based upon our preliminary studies treatments like Autologous, Adipose Derived Stromal Vascular Fraction (SVF) Platelet-Rich Plasma (PRP) Procedures that address tissue defects and/or vascular disease aspects of erectile dysfunction may provide a longer-term therapy.

ED is frequently related to Diabetes?

Erectile dysfunction is significantly common in men who have diabetes which damages nerves and blood vessels. Erectile dysfunction can also be linked to other conditions common in men who have diabetes, such as high blood pressure and coronary artery disease. ED is three times more common in patients with diabetes mellitus. ED in diabetes strongly correlates with the level of glucose control, duration of disease and diabetic complications.

Some other causes of ED other than diabetes are:

  • Metabolic syndrome (a condition involving increased blood pressure, high insulin levels, body fat around the waist and high cholesterol
  • Obesity, chronic inflammation,
  • Low testosterone levels
  • Tobacco; Alcoholism and other drug abuse
  • Heart disease, High blood pressure, neurological disease
  • Peyronie’s disease (development of scar tissue)
  • Parkinson’s disease, Multiple sclerosis disease
  • Surgeries or injuries that affect the pelvic area or spinal cord
  • Medications such as antidepressants, antihistamines and medications to treat high blood pressure, pain or prostate cancer.
  • Emotional or psychological causes including Depression, Stress, anxiety or other mental health conditions

How is Erectile Dysfunction diagnosed?

A comprehensive medical history and a physical exam are needed before we can diagnose and recommend appropriate treatment for ED. Some of the tests that we may do to diagnose the underlying cause of you ED include:

  • Blood tests to check for anemia, diabetes, low hormone levels, liver or kidney disease  and any other medical problems.
  • Tests to diagnose any underlying vascular disease.
  • Ultrasound to check blood flow to your penis. It involves using a wand-like device (transducer) held over the blood vessels that supply the penis.
  • Test for Endothelial Integrity – This test is sometimes done in combination with an Ultrasound to determine if there is an increase in the blood flow in response to the medication.

What are the different approaches for treatment of ED?

Drugs and Medical Treatments for ED – Pharmacological methods have been used to treat erectile dysfunction including the use of vasodilators. Such Nitric Oxide enhance vasodilators include Viagra, Levitra and Cialis. However, vasodilators induce only a temporary response and are not effective in many patients due to the underlying endothelial damage. Not to mention the fact that these medicine can have serious side-effects including heart attack, stroke and may even cause death.

Other options include – Injectable medicine like Alprostadil, Caverjet, Edex, Alprostadil penis suppository intraurethral (MUSE) and Testosterone replacement (cream or injectable). Penile pumps or a vacuum constriction device and Penile Implants may be options for some patients.

Several alternative treatments are used to treat ED, but more studies are needed to see if these are really effective and safe. These options include: Acupuncture, Korean red ginseng (Panax ginseng); Yohimbine; Ginkgo, L-arginine and DHEA (dehydroepiandrosterone). These herbs can be risky and can interact with your medications or cause other problems.

For years the treatment has been either medical/drugs or surgical. Today the Regenerative Medicine may offer a new approach: Stem cells from your own fat or bone marrow, Platelet rich plasma (PRP) from your own blood may enhance the underlying causation factors. The Park Avenue Stem Cell Therapy Center Adult Stem Cell Procedure for ED is still undergoing investigational clinical research using this approach. Because YOUR OWN cells are being used at our clinic, there is very little risk of any transmissible infection or tissue rejection by your body.

Adipose (Fat) Derived Stem Cells – ADSC – Stromal Vascular Fraction (SVF)

Adipose Tissue (Fat) is very rich in stem cells; primarily mesenchymal stem cells. Fat harvesting for ADSC therapy is done with a very simple process called lipoaspiration. It is important to understand that lipoaspiration is vastly different from liposuction. Liposuction removes a very large volume of fat and is intended for a cosmetic result. Lipoaspiration uses a small amount of local anesthetic, a small instrument slightly larger than a hypodermic needle, removes a very small amount of fat (10 – 20cc), and does not render any visible change in appearance. The fat is then concentrated using a simple, sterile gravity method. The entire process is painless and takes under ten minutes.

Platelet-Rich Plasma (PRP)

PRP is an acronym for Platelet Rich Plasma. Plasma is essentially blood without the red blood cells. Platelets are cells found in the blood that are essential for clot formation and wound healing. PRP, the mix of concentrated platelets and serum, contains factors that promote repair of tissues. PRP is injected into the targeted area for repair.

Packed with growth and healing factors, platelets initiate repair and attract the critical assistance of stem cells. PRP therapy’s natural healing process, by providing required growth factors, intensifies the body’s efforts to renew and rejuvenate your aging face. To create PRP therapy, a small sample of your blood is drawn (similar to a lab test sample) and placed in a centrifuge that spins the blood at high speeds, separating the platelets from the other components. The concentrated platelet rich plasma (PRP) is then injected into and around the point of injury, jump-starting and significantly strengthening the body’s natural healing signal.

The Procedure:

During Park Avenue Stem Cell Therapy Center® Procedure for the treatment of ED, we combine your own SVF from fat with PRP. Stem Cells use your body’s own natural reparative factors to harness the healing resources of the body to repair injured tissues. PRP secrete growth factors and send signals which boost the natural healing process in the body. Stem cells not only secrete growth factors and other intercellular signals to command and coordinate the repair process, they can also replace and regenerate tissues by themselves directly.

After we obtain the fatty tissue aspirate and blood, these are then spun in special centrifuge at specific G-force. The stem cells and PRP are then separated respectively. Lipoaspirate is decanted and fat stem cells are then taken out and mixed with PRP. All this is done in strict sterile environment. For most procedures, we blend PRP, and ADSC.

Hormone supplementation

We also use hormone supplementation (only if medically indicated) and Dr. Joel Singer’s specially formulated immune boosting complements before and after this procedure.

Hormone therapy replenishes the hormones our body needs to function properly using various hormones like bioidentical hormones, estrogen, progesterone, testosterone, DHEA, melatonin, pregnenolone, hcg, human growth hormones etc. Through state-of-the-art diagnostic hormone testing, using blood, urine and/or saliva analysis, we can determine your hormone levels and your unique bioidentical hormone needs. Hormones are prescribed ONLY if tests clearly reveal that your body is deficient in hormones.


  • Expect minimal swelling, bruising and redness for 12-24 hours after the procedure. There can also be some pinkness or redness of the skin following the therapy.
  • Treatment results vary and some patients may require PRP booster, however in most patients the results last for several years.

Does it leave scars?

No. There are no scalpel or knives used in the procedure. Specially designed blunt instruments are used to inject the fat and stem cells to sculpt the body areas as desired.

Do I need to be put to asleep?

No. The procedure is minimally invasive and does not require general anesthesia. We use local anesthetic solution (lidocaine) to numb your skin. For very anxious patients, an oral sedative may be given.

Is it safe?

Yes. Since it is your own body’s tissues that we use, there is no allergic or adverse reaction or rejection that can happen from the stem cells. Also, since there is no need for general anesthesia, serious risks associated with general anesthesia and being put to sleep are eliminated.

Is it painful?

Most of my patients report feeling mild pressure during the injection that is controlled with local anesthesia and some soreness in the areas treated for up to 5 to 7 days after the procedure that does not require pain medication.

How long is the recovery?

You will be able to resume your normal daily life immediately, limited by the degree of swelling that you experience after the procedure. Most patients have noticeable swelling in the areas treated from 5 to 7 days depending on the extent of the procedure and individual healing response.

How long will the result last?

The results should last for several years. The results are affected by your lifestyle, habits and genetics. Smoking and weight fluctuations diminish the results.

Is Stem Cell Therapy Approved by FDA?

FDA does not regulate medical procedures performed by qualified and licensed doctors. Currently, there are no clear protocols to treat any disease with adult stem cells in the U.S. We ONLY use your own adult stem cells (not Embryonic stem cells) and we don’t alter or manipulate your cells and we use your cells during the same procedure – therefore FDA does not have oversight to these procedures.

Does insurance cover these procedures? What is the cost?

These procedures are not covered by health insurance plans. With financing, many patients can get Park Avenue Stem Cell Therapy Center Adult Stem Cell Procedures for a minimum investment. There are a variety of different financing options available, and we can help you find the best one for you.

One of the questions that many people have is “how much does this procedure to treat my ED cost?

The cost for our Park Avenue Stem Cell Therapy Center Procedure for ED starts at a very affordable price of $1,500 for PRP injections. We also pre treat with Acoustic Shockwave treatments to get the best outcomes. The cost of Park Avenue Stem Cell Therapy Center Procedure for ED using your own adult stem cells (with PRP) Starts At $9,500 depending on the number of injections needed, severity and duration of the ED, and whether you would need one or more types of stem cells to achieve the best possible results.

Results may vary depending upon the severity of the condition and patient response

A consultation with Dr. Joel Singer, M.D. is needed to decide the best treatment option for you and the exact costs.


Interested in learning more about Stem Cell Therapy? 
Click here for reference articles and studies. 

Park Avenue Stem Cell is not offering stem cell therapy as a cure for any condition, disease, or injury. No statements or implied treatments on this website have been evaluated or approved by the FDA. This website contains no medical advice. All statements and opinions provided by this website are provided for educational and informational purposes only and we do not diagnose or treat via this website or via telephone. We are offering patient funded research to provide individual patients with Stromal Vascular Fraction that contains their own autologous stem cells and growth factors and the treatment centers provide surgical procedures only and are not involved in the use or manufacture of any investigational drugs.

Park Avenue Stem Cell does not claim that any applications, or potential applications, using autologous stem cells are approved by the FDA, or are even effective. We do not claim that these treatments work for any listed nor unlisted condition, intended or implied. It’s important for potential patients to do their own research based on the options that we present so that one can make an informed decision. Any decision to participate in our patient funded experimental protocols is completely voluntary.

ATTENTION: If you have ANY concern with stromal vascular fraction, any of our products, methods, website, or technique and think we may be violating any U.S. law, please contact us so that we can investigate the matter or concern immediately.

**Results of these treatments vary from individual to individual and it is not possible to predict or guarantee the outcome of any medical procedure.


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